High lumenal chloride in the lysosome is critical for lysosome function

Lysosomes are organelles responsible for the breakdown and recycling of cellular machinery. Dysfunctional lysosomes give rise to lysosomal storage disorders as well as common neurodegenerative diseases. Here, we use a DNA-based, fluorescent chloride reporter to measure lysosomal chloride in Caenorha...

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Detalles Bibliográficos
Autores principales: Chakraborty, Kasturi, Leung, KaHo, Krishnan, Yamuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526669/
https://www.ncbi.nlm.nih.gov/pubmed/28742019
http://dx.doi.org/10.7554/eLife.28862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526669/
https://www.ncbi.nlm.nih.gov/pubmed/28742019
http://dx.doi.org/10.7554/eLife.28862

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