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Generation of glyceraldehyde-derived advanced glycation end-products in pancreatic cancer cells and the potential of tumor promotion

AIM: To determine the possibility that diabetes mellitus promotes pancreatic ductal adenocarcinoma via glyceraldehyde (GA)-derived advanced glycation-end products (GA-AGEs). METHODS: PANC-1, a human pancreatic cancer cell line, was treated with 1-4 mmol/L GA for 24 h. The cell viability and intracel...

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Detalles Bibliográficos
Autores principales: Takata, Takanobu, Ueda, Tadashi, Sakasai-Sakai, Akiko, Takeuchi, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526761/
https://www.ncbi.nlm.nih.gov/pubmed/28785145
http://dx.doi.org/10.3748/wjg.v23.i27.4910