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The accessory Sec system (SecY2A2) in Streptococcus pneumoniae is involved in export of pneumolysin toxin, adhesion and biofilm formation

In Streptococcus pneumoniae TIGR4, genes encoding a SecY2A2 accessory Sec system are present within a locus encoding a serine-rich repeat surface protein PsrP. Mutant strains deleted in secA2 or psrP were deficient in biofilm formation, while the ΔsecA2 mutant was reduced in binding to airway epithe...

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Detalles Bibliográficos
Autores principales: Bandara, Mikaila, Skehel, J. Mark, Kadioglu, Aras, Collinson, Ian, Nobbs, Angela H., Blocker, Ariel J., Jenkinson, Howard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526788/
https://www.ncbi.nlm.nih.gov/pubmed/28456649
http://dx.doi.org/10.1016/j.micinf.2017.04.003