Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity

Diabetes and obesity are characterized by insulin resistance and chronic low-grade inflammation. An elevated plasma concentration of lipopolysaccharide (LPS) caused by increased intestinal permeability during diet-induced obesity promotes insulin resistance in mice. Here, we show that LPS induces en...

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Detalles Bibliográficos
Autores principales: Cao, Jia, Peng, Jinghua, An, Hongying, He, Qiyi, Boronina, Tatiana, Guo, Shaodong, White, Morris F., Cole, Philip A., He, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526866/
https://www.ncbi.nlm.nih.gov/pubmed/28743992
http://dx.doi.org/10.1038/s41467-017-00163-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526866/
https://www.ncbi.nlm.nih.gov/pubmed/28743992
http://dx.doi.org/10.1038/s41467-017-00163-w

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