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Covalent, Non-Covalent, Encapsulated Nanodrug Regulate the Fate of Intra- and Extracellular Trafficking: Impact on Cancer and Normal Cells

Drugs need to be designed to access the designated intracellular organelle compartments in order to maximize anticancer efficacy. This study identified that covalently conjugated, non-covalent polyethylene glycol coated and encapsulated nanodrugs selectively influence drug uptake, the intracellular...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Woo, Lee, Yeon Kyung, Kim, Sang-Hyun, Park, Jun-Young, Lee, Dong Un, Choi, Jungil, Hong, Jeong Hee, Kim, Sanghyo, Khang, Dongwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526881/
https://www.ncbi.nlm.nih.gov/pubmed/28743942
http://dx.doi.org/10.1038/s41598-017-06796-7