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Covalent, Non-Covalent, Encapsulated Nanodrug Regulate the Fate of Intra- and Extracellular Trafficking: Impact on Cancer and Normal Cells
Drugs need to be designed to access the designated intracellular organelle compartments in order to maximize anticancer efficacy. This study identified that covalently conjugated, non-covalent polyethylene glycol coated and encapsulated nanodrugs selectively influence drug uptake, the intracellular...
Autores principales: | Kim, Sang-Woo, Lee, Yeon Kyung, Kim, Sang-Hyun, Park, Jun-Young, Lee, Dong Un, Choi, Jungil, Hong, Jeong Hee, Kim, Sanghyo, Khang, Dongwoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526881/ https://www.ncbi.nlm.nih.gov/pubmed/28743942 http://dx.doi.org/10.1038/s41598-017-06796-7 |
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