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Loss of ERα partially reverses the effects of maternal high-fat diet on energy homeostasis in female mice

Maternal high-fat diet (HFD) alters hypothalamic developmental programming and disrupts offspring energy homeostasis in rodents. 17β-estradiol (E2) also influences hypothalamic programming through estrogen receptor (ER) α. Therefore, we hypothesized that females lacking ERα would be more susceptible...

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Detalles Bibliográficos
Autores principales: Roepke, Troy A., Yasrebi, Ali, Villalobos, Alejandra, Krumm, Elizabeth A., Yang, Jennifer A., Mamounis, Kyle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526977/
https://www.ncbi.nlm.nih.gov/pubmed/28743985
http://dx.doi.org/10.1038/s41598-017-06560-x