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Loss of ERα partially reverses the effects of maternal high-fat diet on energy homeostasis in female mice
Maternal high-fat diet (HFD) alters hypothalamic developmental programming and disrupts offspring energy homeostasis in rodents. 17β-estradiol (E2) also influences hypothalamic programming through estrogen receptor (ER) α. Therefore, we hypothesized that females lacking ERα would be more susceptible...
Autores principales: | Roepke, Troy A., Yasrebi, Ali, Villalobos, Alejandra, Krumm, Elizabeth A., Yang, Jennifer A., Mamounis, Kyle J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526977/ https://www.ncbi.nlm.nih.gov/pubmed/28743985 http://dx.doi.org/10.1038/s41598-017-06560-x |
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