Selenocysteine induces apoptosis in human glioma cells: evidence for TrxR1-targeted inhibition and signaling crosstalk

Thioredoxin reductase (TrxR) as a selenium (Se)-containing antioxidase plays key role in regulating intracellular redox status. Selenocystine (SeC) a natural available Se-containing amino acid showed novel anticancer potential through triggering oxidative damage-mediated apoptosis. However, whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Cun-dong, Fu, Xiao-yan, Zhang, Zong-yong, Cao, Ming-zhi, Sun, Jing-yi, Yang, Ming-feng, Fu, Xiao-ting, Zhao, Shi-jun, Shao, Lu-rong, Zhang, Hui-fang, Yang, Xiao-yi, Sun, Bao-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526989/
https://www.ncbi.nlm.nih.gov/pubmed/28743999
http://dx.doi.org/10.1038/s41598-017-06979-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526989/
https://www.ncbi.nlm.nih.gov/pubmed/28743999
http://dx.doi.org/10.1038/s41598-017-06979-2

Ejemplares similares