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Selenocysteine induces apoptosis in human glioma cells: evidence for TrxR1-targeted inhibition and signaling crosstalk

Thioredoxin reductase (TrxR) as a selenium (Se)-containing antioxidase plays key role in regulating intracellular redox status. Selenocystine (SeC) a natural available Se-containing amino acid showed novel anticancer potential through triggering oxidative damage-mediated apoptosis. However, whether...

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Detalles Bibliográficos
Autores principales:	Fan, Cun-dong, Fu, Xiao-yan, Zhang, Zong-yong, Cao, Ming-zhi, Sun, Jing-yi, Yang, Ming-feng, Fu, Xiao-ting, Zhao, Shi-jun, Shao, Lu-rong, Zhang, Hui-fang, Yang, Xiao-yi, Sun, Bao-liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526989/ https://www.ncbi.nlm.nih.gov/pubmed/28743999 http://dx.doi.org/10.1038/s41598-017-06979-2

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