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Chronic activation of JNK JAK/STAT and oxidative stress signalling causes the loser cell status

Cell competition is a form of cell interaction that causes the elimination of less fit cells, or losers, by wild-type (WT) cells, influencing overall tissue health. Several mutations can cause cells to become losers; however, it is not known how. Here we show that Drosophila wing disc cells carrying...

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Detalles Bibliográficos
Autores principales: Kucinski, Iwo, Dinan, Michael, Kolahgar, Golnar, Piddini, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526992/
https://www.ncbi.nlm.nih.gov/pubmed/28743877
http://dx.doi.org/10.1038/s41467-017-00145-y