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Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice
Hematopoietic stem and progenitor cells arise from the vascular endothelium of the dorsal aorta and subsequently switch niche to the fetal liver through unknown mechanisms. Here we report that vascular endothelium-specific deletion of mouse Drosha (Drosha (cKO)), an enzyme essential for microRNA bio...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527007/ https://www.ncbi.nlm.nih.gov/pubmed/28743859 http://dx.doi.org/10.1038/s41467-017-00137-y |