Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice

Hematopoietic stem and progenitor cells arise from the vascular endothelium of the dorsal aorta and subsequently switch niche to the fetal liver through unknown mechanisms. Here we report that vascular endothelium-specific deletion of mouse Drosha (Drosha (cKO)), an enzyme essential for microRNA bio...

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Detalles Bibliográficos
Autores principales: Jiang, Xuan, Hawkins, John S., Lee, Jerry, Lizama, Carlos O., Bos, Frank L., Zape, Joan P., Ghatpande, Prajakta, Peng, Yongbo, Louie, Justin, Lagna, Giorgio, Zovein, Ann C., Hata, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527007/
https://www.ncbi.nlm.nih.gov/pubmed/28743859
http://dx.doi.org/10.1038/s41467-017-00137-y

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