Thrombopoiesis is spatially regulated by the bone marrow vasculature

In mammals, megakaryocytes (MKs) in the bone marrow (BM) produce blood platelets, required for hemostasis and thrombosis. MKs originate from hematopoietic stem cells and are thought to migrate from an endosteal niche towards the vascular sinusoids during their maturation. Through imaging of MKs in t...

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Detalles Bibliográficos
Autores principales: Stegner, David, vanEeuwijk, Judith M. M., Angay, Oğuzhan, Gorelashvili, Maximilian G., Semeniak, Daniela, Pinnecker, Jürgen, Schmithausen, Patrick, Meyer, Imke, Friedrich, Mike, Dütting, Sebastian, Brede, Christian, Beilhack, Andreas, Schulze, Harald, Nieswandt, Bernhard, Heinze, Katrin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527048/
https://www.ncbi.nlm.nih.gov/pubmed/28743899
http://dx.doi.org/10.1038/s41467-017-00201-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527048/
https://www.ncbi.nlm.nih.gov/pubmed/28743899
http://dx.doi.org/10.1038/s41467-017-00201-7

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