Effect of Preventive and Curative Fingolimod Treatment Regimens on Microglia Activation and Disease Progression in a Rat Model of Multiple Sclerosis

Fingolimod was the first oral drug approved for multiple sclerosis treatment. Its principal mechanism of action is blocking of lymphocyte trafficking. In addition, recent studies have shown its capability to diminish microglia activation. The effect of preventive and curative fingolimod treatment on...

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Detalles Bibliográficos
Autores principales: Vállez García, David, Doorduin, Janine, de Paula Faria, Daniele, Dierckx, Rudi A. J. O., de Vries, Erik F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527053/
https://www.ncbi.nlm.nih.gov/pubmed/28361437
http://dx.doi.org/10.1007/s11481-017-9741-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527053/
https://www.ncbi.nlm.nih.gov/pubmed/28361437
http://dx.doi.org/10.1007/s11481-017-9741-x

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