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A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

Endoplasmic reticulum stress is an evolutionarily conserved cell stress response associated with numerous diseases, including cardiac hypertrophy and heart failure. The major endoplasmic reticulum stress signaling pathway causing cardiac hypertrophy involves endoplasmic reticulum stress sensor PERK...

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Detalles Bibliográficos
Autores principales: Yao, Yufeng, Lu, Qiulun, Hu, Zhenkun, Yu, Yubin, Chen, Qiuyun, Wang, Qing K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527107/
https://www.ncbi.nlm.nih.gov/pubmed/28743963
http://dx.doi.org/10.1038/s41467-017-00171-w