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CXCL10 is produced in hepatitis A virus-infected cells in an IRF3-dependent but IFN-independent manner

Acute hepatitis A caused by hepatitis A virus (HAV) infection is accompanied by severe liver injury in adult patients, and the liver injury is associated with the production of chemokines. Herein, we investigated the mechanism of how HAV infection induces the production of CXCR3 and CCR5 chemokines,...

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Detalles Bibliográficos
Autores principales: Sung, Pil Soo, Hong, Seon-Hui, Lee, Jeewon, Park, Su-Hyung, Yoon, Seung Kew, Chung, Woo Jin, Shin, Eui-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527116/
https://www.ncbi.nlm.nih.gov/pubmed/28744018
http://dx.doi.org/10.1038/s41598-017-06784-x