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Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

Estrogen is critical for skeletal homeostasis and regulates bone remodeling, in part, by modulating the expression of receptor activator of NF-κB ligand (RANKL), an essential cytokine for bone resorption by osteoclasts. RANKL can be produced by a variety of hematopoietic (e.g. T and B-cell) and mese...

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Detalles Bibliográficos
Autores principales: Streicher, Carmen, Heyny, Alexandra, Andrukhova, Olena, Haigl, Barbara, Slavic, Svetlana, Schüler, Christiane, Kollmann, Karoline, Kantner, Ingrid, Sexl, Veronika, Kleiter, Miriam, Hofbauer, Lorenz C., Kostenuik, Paul J., Erben, Reinhold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527119/
https://www.ncbi.nlm.nih.gov/pubmed/28744019
http://dx.doi.org/10.1038/s41598-017-06614-0