Traceless Targeting and Isolation of Gene-Edited Immortalized Keratinocytes from Epidermolysis Bullosa Simplex Patients

Epidermolysis bullosa simplex (EBS) is a blistering skin disease caused by dominant-negative mutations in either KRT5 or KRT14, resulting in impairment of keratin filament structure and epidermal fragility. Currently, nearly 200 mutations distributed across the entire length of these genes are known...

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Detalles Bibliográficos
Autores principales: Aushev, Magomet, Koller, Ulrich, Mussolino, Claudio, Cathomen, Toni, Reichelt, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527154/
https://www.ncbi.nlm.nih.gov/pubmed/28765827
http://dx.doi.org/10.1016/j.omtm.2017.06.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527154/
https://www.ncbi.nlm.nih.gov/pubmed/28765827
http://dx.doi.org/10.1016/j.omtm.2017.06.008

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