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Activation of AMPK Attenuated Cardiac Fibrosis by Inhibiting CDK2 via p21/p27 and miR-29 Family Pathways in Rats

Cardiac fibrosis is pathological damage associated with nearly all forms of heart disease. AMP-activated protein kinase (AMPK) is an evolutionary conserved energy-sensing enzyme. Emerging evidences indicate that AMPK plays an important role in cardiac fibrosis and cell proliferation. However, less i...

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Detalles Bibliográficos
Autores principales: Qi, Hanping, Liu, Yan, Li, Shuzhi, Chen, Yunping, Li, Lei, Cao, Yonggang, E, Mingyao, Shi, Pilong, Song, Chao, Li, Baiyan, Sun, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527157/
https://www.ncbi.nlm.nih.gov/pubmed/28918029
http://dx.doi.org/10.1016/j.omtn.2017.07.004