Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival

Although mouse models exist for many immune-based diseases, the clinical translation remains challenging. Most basic and translational studies utilize only a single inbred mouse strain. However, basal and diseased immune states in humans show vast inter-individual variability. Here, focusing on macr...

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Detalles Bibliográficos
Autores principales: Buscher, Konrad, Ehinger, Erik, Gupta, Pritha, Pramod, Akula Bala, Wolf, Dennis, Tweet, George, Pan, Calvin, Mills, Charles D., Lusis, Aldons J., Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527282/
https://www.ncbi.nlm.nih.gov/pubmed/28737175
http://dx.doi.org/10.1038/ncomms16041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527282/
https://www.ncbi.nlm.nih.gov/pubmed/28737175
http://dx.doi.org/10.1038/ncomms16041

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