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Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival
Although mouse models exist for many immune-based diseases, the clinical translation remains challenging. Most basic and translational studies utilize only a single inbred mouse strain. However, basal and diseased immune states in humans show vast inter-individual variability. Here, focusing on macr...
Autores principales: | Buscher, Konrad, Ehinger, Erik, Gupta, Pritha, Pramod, Akula Bala, Wolf, Dennis, Tweet, George, Pan, Calvin, Mills, Charles D., Lusis, Aldons J., Ley, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527282/ https://www.ncbi.nlm.nih.gov/pubmed/28737175 http://dx.doi.org/10.1038/ncomms16041 |
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