Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps

It is generally assumed that the acquisition of antibiotic resistance is associated with a fitness cost. We have shown that overexpression of the MexEF-OprN efflux pump does not decrease the fitness of a resistant Pseudomonas aeruginosa strain compared to its wild-type counterpart. This lack of fitn...

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Detalles Bibliográficos
Autores principales: Olivares Pacheco, Jorge, Alvarez-Ortega, Carolina, Alcalde Rico, Manuel, Martínez, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527304/
https://www.ncbi.nlm.nih.gov/pubmed/28743808
http://dx.doi.org/10.1128/mBio.00500-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527304/
https://www.ncbi.nlm.nih.gov/pubmed/28743808
http://dx.doi.org/10.1128/mBio.00500-17

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