Bacterial Signaling Nucleotides Inhibit Yeast Cell Growth by Impacting Mitochondrial and Other Specifically Eukaryotic Functions

We have engineered Saccharomyces cerevisiae to inducibly synthesize the prokaryotic signaling nucleotides cyclic di-GMP (cdiGMP), cdiAMP, and ppGpp in order to characterize the range of effects these nucleotides exert on eukaryotic cell function during bacterial pathogenesis. Synthetic genetic array...

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Detalles Bibliográficos
Autores principales: Hesketh, Andy, Vergnano, Marta, Wan, Chris, Oliver, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527313/
https://www.ncbi.nlm.nih.gov/pubmed/28743817
http://dx.doi.org/10.1128/mBio.01047-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527313/
https://www.ncbi.nlm.nih.gov/pubmed/28743817
http://dx.doi.org/10.1128/mBio.01047-17

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