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Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q

Endothelial Protein C Receptor (EPCR) is a Major Histocompatibility Complex homologue, with established roles downregulating coagulation and in endothelial protection. Expressed predominantly on endothelium, EPCR affects inflammatory, apoptotic and cell proliferation pathways by binding to activated...

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Detalles Bibliográficos
Autores principales: Lal, Neeraj, Willcox, Carrie R, Beggs, Andrew, Taniere, Philippe, Shikotra, Aarti, Bradding, Peter, Adams, Richard, Fisher, David, Middleton, Gary, Tselepis, Chris, Willcox, Benjamin E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527318/
https://www.ncbi.nlm.nih.gov/pubmed/28770100
http://dx.doi.org/10.1002/cjp2.70