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The role of epithelial–mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel‐resistant prostate cancer

Docetaxel is the main treatment for advanced castration‐resistant prostate cancer; however, resistance eventually occurs. The development of intratumoral drug‐resistant subpopulations possessing a cancer stem cell (CSC) morphology is an emerging mechanism of docetaxel resistance, a process driven by...

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Detalles Bibliográficos
Autores principales: Hanrahan, Karen, O'Neill, Amanda, Prencipe, Maria, Bugler, Jane, Murphy, Lisa, Fabre, Aurelie, Puhr, Martin, Culig, Zoran, Murphy, Keefe, Watson, R. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527446/
https://www.ncbi.nlm.nih.gov/pubmed/28133913
http://dx.doi.org/10.1002/1878-0261.12030