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Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis

The 4-aminoquinoline chloroquine (CQ) is clinically used in combination with doxycycline to cure chronic Q fever, as it enhances the activity of the antibiotic against the causative bacterium Coxiella burnetii residing within macrophage phagolysosomes. As there is a similar cellular host-pathogen bi...

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Detalles Bibliográficos
Autores principales: Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Yardley, Vanessa, Murdan, Sudaxshina, Croft, Simon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527568/
https://www.ncbi.nlm.nih.gov/pubmed/28607026
http://dx.doi.org/10.1128/AAC.00358-17