Hepatitis B Virus Capsid Assembly Modulators, but Not Nucleoside Analogs, Inhibit the Production of Extracellular Pregenomic RNA and Spliced RNA Variants

The hepatitis B virus (HBV) core protein serves multiple essential functions in the viral life cycle, and antiviral agents that target the core protein are being developed. Capsid assembly modulators (CAMs) are compounds that target core and misdirect capsid assembly, resulting in the suppression of...

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Detalles Bibliográficos
Autores principales: Lam, Angela M., Ren, Suping, Espiritu, Christine, Kelly, Mollie, Lau, Vincent, Zheng, Lingjie, Hartman, George D., Flores, Osvaldo A., Klumpp, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527605/
https://www.ncbi.nlm.nih.gov/pubmed/28559265
http://dx.doi.org/10.1128/AAC.00680-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527605/
https://www.ncbi.nlm.nih.gov/pubmed/28559265
http://dx.doi.org/10.1128/AAC.00680-17

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