Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing

Nitroreductase enzymes are responsible for the reduction of nitro functional groups to amino functional groups, and are found in a range of animal models, zebrafish (Danio rerio) excluded. Transgenic zebrafish models have been developed for tissue-specific cell ablation, which use nitroreductase to...

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Detalles Bibliográficos
Autores principales: Chlebowski, Anna C., La Du, Jane K., Truong, Lisa, Massey Simonich, Staci L., Tanguay, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527975/
https://www.ncbi.nlm.nih.gov/pubmed/28758069
http://dx.doi.org/10.1016/j.toxrep.2017.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527975/
https://www.ncbi.nlm.nih.gov/pubmed/28758069
http://dx.doi.org/10.1016/j.toxrep.2017.04.005

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