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Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing
Nitroreductase enzymes are responsible for the reduction of nitro functional groups to amino functional groups, and are found in a range of animal models, zebrafish (Danio rerio) excluded. Transgenic zebrafish models have been developed for tissue-specific cell ablation, which use nitroreductase to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527975/ https://www.ncbi.nlm.nih.gov/pubmed/28758069 http://dx.doi.org/10.1016/j.toxrep.2017.04.005 |