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WNT‐5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells

An important role for WNT‐5A is implicated in a variety of tumors, including breast carcinoma. We previously showed that WNT‐5A signaling inhibits migration and metastasis of breast cancer cells, and that patients with primary breast cancer in which WNT‐5A was expressed have a better prognosis. Desp...

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Detalles Bibliográficos
Autores principales: Prasad, Chandra Prakash, Chaurasiya, Shivendra Kumar, Axelsson, Lena, Andersson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528454/
https://www.ncbi.nlm.nih.gov/pubmed/23727359
http://dx.doi.org/10.1016/j.molonc.2013.04.005