Secretome and degradome profiling shows that Kallikrein‐related peptidases 4, 5, 6, and 7 induce TGFβ‐1 signaling in ovarian cancer cells

Kallikrein‐related peptidases, in particular KLK4, 5, 6 and 7 (4–7), often have elevated expression levels in ovarian cancer. In OV‐MZ‐6 ovarian cancer cells, combined expression of KLK4–7 reduces cell adhesion and increases cell invasion and resistance to paclitaxel. The present work investigates h...

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Detalles Bibliográficos
Autores principales: Shahinian, Hasmik, Loessner, Daniela, Biniossek, Martin L., Kizhakkedathu, Jayachandran N., Clements, Judith A., Magdolen, Viktor, Schilling, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528505/
https://www.ncbi.nlm.nih.gov/pubmed/24120346
http://dx.doi.org/10.1016/j.molonc.2013.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528505/
https://www.ncbi.nlm.nih.gov/pubmed/24120346
http://dx.doi.org/10.1016/j.molonc.2013.09.003

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