Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers

The use of immunohistochemistry (IHC) in clinical cohorts is of paramount importance in determining the utility of a biomarker in clinical practice. A major bottleneck in translating a biomarker from bench‐to‐bedside is the lack of well characterized, specific antibodies suitable for IHC. Despite th...

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Detalles Bibliográficos
Autores principales: O'Hurley, Gillian, Sjöstedt, Evelina, Rahman, Arman, Li, Bo, Kampf, Caroline, Pontén, Fredrik, Gallagher, William M., Lindskog, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528533/
https://www.ncbi.nlm.nih.gov/pubmed/24725481
http://dx.doi.org/10.1016/j.molonc.2014.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528533/
https://www.ncbi.nlm.nih.gov/pubmed/24725481
http://dx.doi.org/10.1016/j.molonc.2014.03.008

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