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Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers
The use of immunohistochemistry (IHC) in clinical cohorts is of paramount importance in determining the utility of a biomarker in clinical practice. A major bottleneck in translating a biomarker from bench‐to‐bedside is the lack of well characterized, specific antibodies suitable for IHC. Despite th...
Autores principales: | O'Hurley, Gillian, Sjöstedt, Evelina, Rahman, Arman, Li, Bo, Kampf, Caroline, Pontén, Fredrik, Gallagher, William M., Lindskog, Cecilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528533/ https://www.ncbi.nlm.nih.gov/pubmed/24725481 http://dx.doi.org/10.1016/j.molonc.2014.03.008 |
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