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Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse

Patient derived xenografts (PDXs) are increasingly appreciated models in cancer research, particularly for preclinical testing, as they reflect the patient's tumor biology more accurately than cancer cell lines. We have established a collection of 20 breast PDXs and characterized their biologic...

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Detalles Bibliográficos
Autores principales: du Manoir, Stanislas, Orsetti, Béatrice, Bras-Gonçalves, Rui, Nguyen, Tien-Tuan, Lasorsa, Laurence, Boissière, Florence, Massemin, Blandine, Colombo, Pierre-Emmanuel, Bibeau, Frédéric, Jacot, William, Theillet, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528550/
https://www.ncbi.nlm.nih.gov/pubmed/24394560
http://dx.doi.org/10.1016/j.molonc.2013.11.010