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Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse
Patient derived xenografts (PDXs) are increasingly appreciated models in cancer research, particularly for preclinical testing, as they reflect the patient's tumor biology more accurately than cancer cell lines. We have established a collection of 20 breast PDXs and characterized their biologic...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528550/ https://www.ncbi.nlm.nih.gov/pubmed/24394560 http://dx.doi.org/10.1016/j.molonc.2013.11.010 |