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Interleukin‐6 drives melanoma cell motility through p38α‐MAPK‐dependent up‐regulation of WNT5A expression

Extensive research has demonstrated a tumor‐promoting role of increased WNT5A expression in malignant melanoma. However, very little light has been shed upon how WNT5A expression is up‐regulated in melanoma. A potential regulator of WNT5A expression is the pro‐inflammatory cytokine Interleukin (IL)‐...

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Detalles Bibliográficos
Autores principales: Linnskog, Rickard, Jönsson, Gunilla, Axelsson, Lena, Prasad, Chandra P., Andersson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528610/
https://www.ncbi.nlm.nih.gov/pubmed/24954857
http://dx.doi.org/10.1016/j.molonc.2014.05.008