Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

Both Myc and Ras oncogenes impact cellular metabolism, deregulate redox homeostasis and trigger DNA replication stress (RS) that compromises genomic integrity. However, how are such oncogene‐induced effects evoked and temporally related, to what extent are these kinetic parameters shared by Myc and...

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Detalles Bibliográficos
Autores principales: Maya-Mendoza, Apolinar, Ostrakova, Jitka, Kosar, Martin, Hall, Arnaldur, Duskova, Pavlina, Mistrik, Martin, Merchut-Maya, Joanna Maria, Hodny, Zdenek, Bartkova, Jirina, Christensen, Claus, Bartek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528704/
https://www.ncbi.nlm.nih.gov/pubmed/25435281
http://dx.doi.org/10.1016/j.molonc.2014.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528704/
https://www.ncbi.nlm.nih.gov/pubmed/25435281
http://dx.doi.org/10.1016/j.molonc.2014.11.001

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