Robust BRCA1‐like classification of copy number profiles of samples repeated across different datasets and platforms

Breast cancers with BRCA1 germline mutation have a characteristic DNA copy number (CN) pattern. We developed a test that assigns CN profiles to be ‘BRCA1‐like’ or ‘non‐BRCA1‐like’, which refers to resembling a BRCA1‐mutated tumor or resembling a tumor without a BRCA1 mutation, respectively. Approxim...

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Detalles Bibliográficos
Autores principales: Schouten, Philip C., Grigoriadis, Anita, Kuilman, Thomas, Mirza, Hasan, Watkins, Johnathan A., Cooke, Saskia A., van Dyk, Ewald, Severson, Tesa M., Rueda, Oscar M., Hoogstraat, Marlous, Verhagen, Caroline V.M., Natrajan, Rachael, Chin, Suet-Feung, Lips, Esther H., Kruizinga, Janneke, Velds, Arno, Nieuwland, Marja, Kerkhoven, Ron M., Krijgsman, Oscar, Vens, Conchita, Peeper, Daniel, Nederlof, Petra M., Caldas, Carlos, Tutt, Andrew N., Wessels, Lodewyk F., Linn, Sabine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528812/
https://www.ncbi.nlm.nih.gov/pubmed/25825120
http://dx.doi.org/10.1016/j.molonc.2015.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528812/
https://www.ncbi.nlm.nih.gov/pubmed/25825120
http://dx.doi.org/10.1016/j.molonc.2015.03.002

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