MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors

Little structural information is available so far on amyloid fibrils consisting of immunoglobulin light chains. It is not understood which features of the primary sequence of the protein result in fibril formation. We report here MAS solid-state NMR studies to identify the structured core of κ-type...

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Detalles Bibliográficos
Autores principales: Hora, Manuel, Sarkar, Riddhiman, Morris, Vanessa, Xue, Kai, Prade, Elke, Harding, Emma, Buchner, Johannes, Reif, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528828/
https://www.ncbi.nlm.nih.gov/pubmed/28746363
http://dx.doi.org/10.1371/journal.pone.0181799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528828/
https://www.ncbi.nlm.nih.gov/pubmed/28746363
http://dx.doi.org/10.1371/journal.pone.0181799

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