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The mechanism of monomer transfer between two structurally distinct PrP oligomers

In mammals, Prion pathology refers to a class of infectious neuropathologies whose mechanism is based on the self-perpetuation of structural information stored in the pathological conformer. The characterisation of the PrP folding landscape has revealed the existence of a plethora of pathways conduc...

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Detalles Bibliográficos
Autores principales: Armiento, Aurora, Moireau, Philippe, Martin, Davy, Lepejova, Nad’a, Doumic, Marie, Rezaei, Human
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528842/
https://www.ncbi.nlm.nih.gov/pubmed/28746342
http://dx.doi.org/10.1371/journal.pone.0180538