Dystrophin Glycoprotein Complex Sequesters Yap to Inhibit Cardiomyocyte Proliferation

The regenerative capacity of the adult mammalian heart is limited because of the reduced ability of cardiomyocytes (CMs) to progress through mitosis(1). The regenerative capacity of endogenous CMs exists at birth but is lost postnatally, with subsequent organ growth occurring through CM hypertrophy(...

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Detalles Bibliográficos
Autores principales: Morikawa, Yuka, Heallen, Todd, Leach, John, Xiao, Yang, Martin, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528853/
https://www.ncbi.nlm.nih.gov/pubmed/28581498
http://dx.doi.org/10.1038/nature22979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528853/
https://www.ncbi.nlm.nih.gov/pubmed/28581498
http://dx.doi.org/10.1038/nature22979

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