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Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G(2)/M cell cycle arrest

The efficacy of cisplatin-based chemotherapy in cancer is limited by the occurrence of innate and acquired drug resistance. In order to better understand the mechanisms underlying acquired cisplatin resistance, we have compared the adenocarcinoma-derived non-small cell lung cancer (NSCLC) cell line...

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Detalles Bibliográficos
Autores principales: Sarin, Navin, Engel, Florian, Kalayda, Ganna V., Mannewitz, Mareike, Cinatl, Jindrich, Rothweiler, Florian, Michaelis, Martin, Saafan, Hisham, Ritter, Christoph A., Jaehde, Ulrich, Frötschl, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528889/
https://www.ncbi.nlm.nih.gov/pubmed/28746345
http://dx.doi.org/10.1371/journal.pone.0181081