Conversion to stem‐cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells

Cancer cells within a tumor are functionally heterogeneous and specific subpopulations, defined as cancer initiating cells (CICs), are endowed with higher tumor forming potential. The CIC state, however, is not hierarchically stable and conversion of non‐CICs to CICs under microenvironment signals m...

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Detalles Bibliográficos
Autores principales: Andriani, Francesca, Bertolini, Giulia, Facchinetti, Federica, Baldoli, Erika, Moro, Massimo, Casalini, Patrizia, Caserini, Roberto, Milione, Massimo, Leone, Giorgia, Pelosi, Giuseppe, Pastorino, Ugo, Sozzi, Gabriella, Roz, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528953/
https://www.ncbi.nlm.nih.gov/pubmed/26514616
http://dx.doi.org/10.1016/j.molonc.2015.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528953/
https://www.ncbi.nlm.nih.gov/pubmed/26514616
http://dx.doi.org/10.1016/j.molonc.2015.10.002

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