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Conversion to stem‐cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells
Cancer cells within a tumor are functionally heterogeneous and specific subpopulations, defined as cancer initiating cells (CICs), are endowed with higher tumor forming potential. The CIC state, however, is not hierarchically stable and conversion of non‐CICs to CICs under microenvironment signals m...
Autores principales: | Andriani, Francesca, Bertolini, Giulia, Facchinetti, Federica, Baldoli, Erika, Moro, Massimo, Casalini, Patrizia, Caserini, Roberto, Milione, Massimo, Leone, Giorgia, Pelosi, Giuseppe, Pastorino, Ugo, Sozzi, Gabriella, Roz, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528953/ https://www.ncbi.nlm.nih.gov/pubmed/26514616 http://dx.doi.org/10.1016/j.molonc.2015.10.002 |
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