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High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/fa(CP) rats, a model of type 2 diabetic nephropathy
ZSF1 rats exhibit spontaneous nephropathy secondary to obesity, hypertension, and diabetes, and have gained interest as a model system with potentially high translational value to progressive human disease. To thoroughly characterize this model, and to better understand how closely it recapitulates...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529026/ https://www.ncbi.nlm.nih.gov/pubmed/28746409 http://dx.doi.org/10.1371/journal.pone.0181861 |