High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/fa(CP) rats, a model of type 2 diabetic nephropathy

ZSF1 rats exhibit spontaneous nephropathy secondary to obesity, hypertension, and diabetes, and have gained interest as a model system with potentially high translational value to progressive human disease. To thoroughly characterize this model, and to better understand how closely it recapitulates...

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Detalles Bibliográficos
Autores principales: Dower, Ken, Zhao, Shanrong, Schlerman, Franklin J., Savary, Leigh, Campanholle, Gabriela, Johnson, Bryce G., Xi, Li, Nguyen, Vuong, Zhan, Yutian, Lech, Matthew P., Wang, Ju, Nie, Qing, Karsdal, Morten A., Genovese, Federica, Boucher, Germaine, Brown, Thomas P., Zhang, Baohong, Homer, Bruce L., Martinez, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529026/
https://www.ncbi.nlm.nih.gov/pubmed/28746409
http://dx.doi.org/10.1371/journal.pone.0181861

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