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A viral scaffolding protein triggers portal ring oligomerization and incorporation during procapsid assembly

Most double-stranded DNA viruses package genetic material into empty precursor capsids (or procapsids) through a dodecameric portal protein complex that occupies 1 of the 12 vertices of the icosahedral lattice. Inhibiting incorporation of the portal complex prevents the formation of infectious virio...

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Detalles Bibliográficos
Autores principales: Motwani, Tina, Lokareddy, Ravi K., Dunbar, Carmen A., Cortines, Juliana R., Jarrold, Martin F., Cingolani, Gino, Teschke, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529062/
https://www.ncbi.nlm.nih.gov/pubmed/28782023
http://dx.doi.org/10.1126/sciadv.1700423