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A viral scaffolding protein triggers portal ring oligomerization and incorporation during procapsid assembly
Most double-stranded DNA viruses package genetic material into empty precursor capsids (or procapsids) through a dodecameric portal protein complex that occupies 1 of the 12 vertices of the icosahedral lattice. Inhibiting incorporation of the portal complex prevents the formation of infectious virio...
Autores principales: | Motwani, Tina, Lokareddy, Ravi K., Dunbar, Carmen A., Cortines, Juliana R., Jarrold, Martin F., Cingolani, Gino, Teschke, Carolyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529062/ https://www.ncbi.nlm.nih.gov/pubmed/28782023 http://dx.doi.org/10.1126/sciadv.1700423 |
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