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Comparative Visualization of the RNA Suboptimal Conformational Ensemble In Vivo

When a ribonucleic acid (RNA) molecule folds, it often does not adopt a single, well-defined conformation. The folding energy landscape of an RNA is highly dependent on its nucleotide sequence and molecular environment. Cellular molecules sometimes alter the energy landscape, thereby changing the en...

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Detalles Bibliográficos
Autores principales: Woods, Chanin T., Lackey, Lela, Williams, Benfeard, Dokholyan, Nikolay V., Gotz, David, Laederach, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529173/
https://www.ncbi.nlm.nih.gov/pubmed/28625696
http://dx.doi.org/10.1016/j.bpj.2017.05.031