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Comparative Visualization of the RNA Suboptimal Conformational Ensemble In Vivo
When a ribonucleic acid (RNA) molecule folds, it often does not adopt a single, well-defined conformation. The folding energy landscape of an RNA is highly dependent on its nucleotide sequence and molecular environment. Cellular molecules sometimes alter the energy landscape, thereby changing the en...
Autores principales: | Woods, Chanin T., Lackey, Lela, Williams, Benfeard, Dokholyan, Nikolay V., Gotz, David, Laederach, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529173/ https://www.ncbi.nlm.nih.gov/pubmed/28625696 http://dx.doi.org/10.1016/j.bpj.2017.05.031 |
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